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Functional expression of a penicillin acylase from the extreme thermophile Thermus thermophilus HB27 in Escherichia coli

BACKGROUND: Penicillin acylases (PACs) are enzymes of industrial relevance in the manufacture of β-lactam antibiotics. Development of a PAC with a longer half-life under the reaction conditions used is essential for the improvement of the operational stability of the process. A gene encoding a homol...

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Bibliografske podrobnosti
Main Authors: Torres, Leticia L, Ferreras, Eloy R, Cantero, Ángel, Hidalgo, Aurelio, Berenguer, José
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3461476/
https://ncbi.nlm.nih.gov/pubmed/22876915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-105
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