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Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice
Abstract Background Treatment with the α-glucosidase inhibitor acarbose increases median lifespan by approximately 20% in male mice and 5% in females. This longevity extension differs from dietary restriction based on a number of features, including the relatively small effects on weight and the sex...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2019-06-01
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| Colecção: | BMC Microbiology |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s12866-019-1494-7 |
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