Resultados da busca - Randy Strong

Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update por Zelton Dave Sharp, Randy Strong

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Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. por Smita Majumder, Arlan Richardson, Randy Strong, Salvatore Oddo

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Nuclei Isolation from Bone Cells for Nuclear Run-on Assays por Narayanasamy Elango, Jeevalatha Vivekananda, Randy Strong, Michael S. Katz

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NIA Interventions Testing Program: Investigating Putative Aging Intervention Agents in a Genetically Heterogeneous Mouse Model por Nancy L. Nadon, Randy Strong, Richard A. Miller, David E. Harrison

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Deciphering the timing and impact of life-extending interventions: temporal efficacy profiler distinguishes early, midlife, and senescence phase efficacies por Nisi Jiang, Catherine J. Cheng, Qianqian Liu, Randy Strong, Jonathan Gelfond, James F. Nelson

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Dexamethasone Causes Hypertension in Rats Even Under Chemical Blockade of Peripheral Sympathetic Nerves por Alexandra E. Soto-Piña, Cynthia Franklin, C. S. Sheela Rani, C. S. Sheela Rani, Elizabeth Fernandez, Elizabeth Fernandez, Elías Cardoso-Peña, Alejandra D. Benítez-Arciniega, Helmut Gottlieb, Carmen Hinojosa-Laborde, Randy Strong, Randy Strong

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Neurodegeneration and motor dysfunction in mice lacking cytosolic and mitochondrial aldehyde dehydrogenases: implications for Parkinson's disease. por Margaret Chia-Ying Wey, Elizabeth Fernandez, Paul Anthony Martinez, Patricia Sullivan, David S Goldstein, Randy Strong

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Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice por Byron J Smith, Richard A Miller, Aaron C Ericsson, David C Harrison, Randy Strong, Thomas M Schmidt

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Cognitive dysfunction precedes the onset of motor symptoms in the MitoPark mouse model of Parkinson's disease. por Xiuhua Li, Laney Redus, Cang Chen, Paul A Martinez, Randy Strong, Senlin Li, Jason C O'Connor

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Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. por Patricia Spilman, Natalia Podlutskaya, Matthew J Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan

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Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease. por Patricia Spilman, Natalia Podlutskaya, Matthew J. Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan

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Correction: Inhibition of mTOR by Rapamycin Abolishes Cognitive Deficits and Reduces Amyloid-β Levels in a Mouse Model of Alzheimer's Disease. por Patricia Spilman, Natalia Podlutskaya, Matthew J. Hart, Jayanta Debnath, Olivia Gorostiza, Dale Bredesen, Arlan Richardson, Randy Strong, Veronica Galvan

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Development of primary osteoarthritis during aging in genetically diverse UM-HET3 mice por Sher Bahadur Poudel, Ryan R. Ruff, Gozde Yildirim, Richard A. Miller, David E. Harrison, Randy Strong, Thorsten Kirsch, Shoshana Yakar

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Impaired aldehyde detoxification exacerbates motor deficits in an alpha‐synuclein mouse model of Parkinson's disease por Paul Anthony Martinez, Vanessa Elia Martinez, Sheela Rani, Meredith Murrell, Martin Javors, Jonathan Gelfond, Jonathan Alan Doorn, Elizabeth Fernandez, Randy Strong

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DOPAL initiates αSynuclein-dependent impaired proteostasis and degeneration of neuronal projections in Parkinson’s disease por Anna Masato, Nicoletta Plotegher, Francesca Terrin, Michele Sandre, Gaia Faustini, Andrea Thor, Stephen Adams, Giulia Berti, Susanna Cogo, Federica De Lazzari, Camilla Maria Fontana, Paul Anthony Martinez, Randy Strong, Rina Bandopadhyay, Marco Bisaglia, Arianna Bellucci, Elisa Greggio, Luisa Dalla Valle, Daniela Boassa, Luigi Bubacco

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Canagliflozin extends life span in genetically heterogeneous male but not female mice por Richard A. Miller, David E. Harrison, David B. Allison, Molly Bogue, Lucas Debarba, Vivian Diaz, Elizabeth Fernandez, Andrzej Galecki, W. Timothy Garvey, Hashan Jayarathne, Navasuja Kumar, Martin A. Javors, Warren C. Ladiges, Francesca Macchiarini, James Nelson, Peter Reifsnyder, Nadia A. Rosenthal, Marianna Sadagurski, Adam B. Salmon, Daniel L. Smith Jr., Jessica M. Snyder, David B. Lombard, Randy Strong

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