Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytes

INTRODUCTION: Insulin-like growth factor I (IGF-I) regulates articular cartilage homeostasis. During osteoarthritis (OA), the anabolic responses of chondrocytes to IGF-I are likely to be prevented by the enhanced production of IGF-binding proteins (IGFBPs), especially IGFBP-3. The aim of this study...

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Bibliografski detalji
Glavni autori: Gasparini, Giorgio, De Gori, Marco, Paonessa, Francesco, Chiefari, Eusebio, Brunetti, Antonio, Galasso, Olimpio
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2012
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580519/
https://ncbi.nlm.nih.gov/pubmed/23036517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4045
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