Derivation of HLA types from shotgun sequence datasets

The human leukocyte antigen (HLA) is key to many aspects of human physiology and medicine. All current sequence-based HLA typing methodologies are targeted approaches requiring the amplification of specific HLA gene segments. Whole genome, exome and transcriptome shotgun sequencing can generate prod...

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Autors principals: Warren, René L, Choe, Gina, Freeman, Douglas J, Castellarin, Mauro, Munro, Sarah, Moore, Richard, Holt, Robert A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Method
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580435/
https://ncbi.nlm.nih.gov/pubmed/23228053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm396
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