Tie2(+) Bone Marrow Endothelial Cells Regulate Hematopoietic Stem Cell Regeneration Following Radiation Injury

Hematopoietic stem cells (HSCs) reside in proximity to bone marrow endothelial cells (BM ECs) and maintenance of the HSC pool is dependent upon EC-mediated c-kit signaling. Here, we utilized genetic models to determine if radioprotection of BM ECs could facilitate hematopoietic regeneration followin...

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Autores principales: Doan, Phuong L., Russell, J. Lauren, Himburg, Heather A., Helms, Katherine, Harris, Jeffrey, Lucas, Joseph, Holshausen, Kirsten, Meadows, Sarah K., Daher, Pamela, Jeffords, Laura B., Chao, Nelson J., Kirsch, David G., Chute, John P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580267/
https://ncbi.nlm.nih.gov/pubmed/23132593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1275
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