High-Throughput Screening for Growth Inhibitors Using a Yeast Model of Familial Paraganglioma

Classical tumor suppressor genes block neoplasia by regulating cell growth and death. A remarkable puzzle is therefore presented by familial paraganglioma (PGL), a neuroendocrine cancer where the tumor suppressor genes encode subunits of succinate dehydrogenase (SDH), an enzyme of the tricarboxylic...

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Main Authors: Bancos, Irina, Bida, John Paul, Tian, Defeng, Bundrick, Mary, John, Kristen, Holte, Molly Nelson, Her, Yeng F., Evans, Debra, Saenz, Dyana T., Poeschla, Eric M., Hook, Derek, Georg, Gunda, Maher, L. James
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579935/
https://ncbi.nlm.nih.gov/pubmed/23451094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056827
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