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Characterization of anti-NF-κB RNA aptamer-binding specificity in vitro and in the yeast three-hybrid system

RNA aptamers offer a potential therapeutic approach to the competitive inhibition of DNA-binding transcription factors. In previous reports we described in vitro selection and characterization of anti-NF-κB p50 and p65 RNA aptamers. We now describe the further characterization of these aptamers in v...

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Detalhes bibliográficos
Main Authors: Wurster, Susan E., Bida, John Paul, Her, Yeng F., Maher, L. James
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764441/
https://ncbi.nlm.nih.gov/pubmed/19696077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp670
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