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Oxygen Concentration Controls Epigenetic Effects in Models of Familial Paraganglioma

Familial paraganglioma (PGL) is a rare neuroendocrine cancer associated with defects in the genes encoding the subunits of succinate dehydrogenase (SDH), a tricarboxylic acid (TCA) cycle enzyme. For unknown reasons, a higher prevalence of PGL has been reported for humans living at higher altitude, w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Her, Yeng F., Nelson-Holte, Molly, Maher, Louis James
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436181/
https://ncbi.nlm.nih.gov/pubmed/25985299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127471
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