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Modeling dioxygenase enzyme kinetics in familial paraganglioma

Hypoxia inducible factors (HIFs) play vital roles in cellular maintenance of oxygen homeostasis. These transcription factors are responsible for the expression of genes involved in angiogenesis, metabolism, and cell proliferation. Here, we generate a detailed mathematical model for the enzyme kineti...

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Detalles Bibliográficos
Publicado en:Biol Open
Main Authors: Peters, Justin P., Her, Yeng F., Maher, L. James
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610226/
https://ncbi.nlm.nih.gov/pubmed/26369930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.013623
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