Mitotic Arrest and Apoptosis in Breast Cancer Cells Induced by Origanum majorana Extract: Upregulation of TNF-α and Downregulation of Survivin and Mutant p53

BACKGROUND: In the present study, we investigated the effect of Origanum majorana ethanolic extract on the survival of the highly proliferative and invasive triple-negative p53 mutant breast cancer cell line MDA-MB-231. RESULTS: We found that O. majorana extract (OME) was able to inhibit the viabili...

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Detalhes bibliográficos
Main Authors: Al Dhaheri, Yusra, Eid, Ali, AbuQamar, Synan, Attoub, Samir, Khasawneh, Mohammad, Aiche, Ghenima, Hisaindee, Soleiman, Iratni, Rabah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579842/
https://ncbi.nlm.nih.gov/pubmed/23451065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056649
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