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Measuring Rates of Ubiquitin Chain Formation as a Functional Readout of Ligase Activity

Specificity within the pathways of ubiquitin conjugation are defined by protein-binding affinities among the components. Enzyme kinetics provides a facile high-resolution experimental approach for quantitating such protein-binding affinities and yields additional mechanistic insights into the transi...

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Detaylı Bibliyografya
Asıl Yazarlar: Ronchi, Virginia P., Haas, Arthur L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579653/
https://ncbi.nlm.nih.gov/pubmed/22350887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-474-2_14
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