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Anti-IL-5 attenuates activation and surface density of β(2)-integrins on circulating eosinophils after segmental antigen challenge
BACKGROUND: IL-5 activates α(M)β(2) integrin on blood eosinophils in vitro. Eosinophils in bronchoalveolar lavage (BAL) following segmental antigen challenge have activated β(2)-integrins. OBJECTIVE: To identify roles for IL-5 in regulating human eosinophil integrins in vivo. METHODS: Blood and BAL...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579563/ https://ncbi.nlm.nih.gov/pubmed/23414537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2012.04065.x |
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