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A Class of 5-Nitro-2-furancarboxylamides with Potent Trypanocidal Activity against Trypanosoma brucei in Vitro

[Image: see text] Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for this and associated diseases. In this study, we have synthesized a series of nove...

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Autori principali: Zhou, Linna, Stewart, Gavin, Rideau, Emeline, Westwood, Nicholas J., Smith, Terry K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2013
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579312/
https://ncbi.nlm.nih.gov/pubmed/23281892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301215e
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