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A Class of 5-Nitro-2-furancarboxylamides with Potent Trypanocidal Activity against Trypanosoma brucei in Vitro

[Image: see text] Recently, the World Health Organization approved the nifurtimox–eflornithine combination therapy for the treatment of human African trypanosomiasis, renewing interest in nitroheterocycle therapies for this and associated diseases. In this study, we have synthesized a series of nove...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhou, Linna, Stewart, Gavin, Rideau, Emeline, Westwood, Nicholas J., Smith, Terry K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2013
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579312/
https://ncbi.nlm.nih.gov/pubmed/23281892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm301215e
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