Association between eIF3α polymorphism and severe toxicity caused by platinum-based chemotherapy in non-small cell lung cancer patients

AIM: Platinum-induced toxicity severely impedes successful chemotherapy in lung cancer patients. The nucleotide excision repair (NER) pathway is considered as one of the major factors contributing to platinum effects. Furthermore, genetic variances of the NER pathway influence platinum toxicity. eIF...

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Main Authors: Xu, Xiaojing, Han, Lifang, Duan, Li, Zhao, Yingchun, Yang, Huaping, Zhou, Boting, Ma, Rui, Yuan, Ruixia, Zhou, Honghao, Liu, Zhaoqian
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Pharmacogenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579266/
https://ncbi.nlm.nih.gov/pubmed/22804784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04379.x
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