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Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patients

AIM: Eukaryotic translation initiation factor 3 subunit A (eIF3a) plays critical roles in regulating the initiation of protein translation, and eIF3a is highly expressed in lung cancer. In this study, we investigated the association of the positively selected SNPs of eIF3a with the response to and t...

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Publicat a:Acta Pharmacol Sin
Autors principals: Yin, Ji-ye, Meng, Xiang-guang, Qian, Chen-yue, Li, Xiang-ping, Chen, Juan, Zheng, Yi, Liu, Rong, Zhou, Hong-hao, Liu, Zhao-qian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349930/
https://ncbi.nlm.nih.gov/pubmed/25732572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.160
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