Association of positively selected eIF3a polymorphisms with toxicity of platinum-based chemotherapy in NSCLC patients

AIM: Eukaryotic translation initiation factor 3 subunit A (eIF3a) plays critical roles in regulating the initiation of protein translation, and eIF3a is highly expressed in lung cancer. In this study, we investigated the association of the positively selected SNPs of eIF3a with the response to and t...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Yin, Ji-ye, Meng, Xiang-guang, Qian, Chen-yue, Li, Xiang-ping, Chen, Juan, Zheng, Yi, Liu, Rong, Zhou, Hong-hao, Liu, Zhao-qian
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349930/
https://ncbi.nlm.nih.gov/pubmed/25732572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.160
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