Assessment of potential drug interactions by characterization of human drug metabolism pathways using non-invasive bile sampling

AIM: Characterization of the biliary disposition of GSK1325756, using a non-invasive bile sampling technique and spectrometric analyses, to inform the major routes of metabolic elimination and to enable an assessment of victim drug interaction risk. METHOD: Sixteen healthy, elderly subjects underwen...

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Hlavní autoři: Bloomer, Jackie C, Nash, Mike, Webb, Alison, Miller, Bruce E, Lazaar, Aili L, Beaumont, Claire, Guiney, William J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2013
Témata:
Drug Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579263/
https://ncbi.nlm.nih.gov/pubmed/22670830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04352.x
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