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Trypanosoma cruzi Coaxes Cardiac Fibroblasts into Preventing Cardiomyocyte Death by Activating Nerve Growth Factor Receptor TrkA

RATIONALE: Cardiomyocytes express neurotrophin receptor TrkA that promotes survival following nerve growth factor (NGF) ligation. Whether TrkA also resides in cardiac fibroblasts (CFs) and underlies cardioprotection is unknown. OBJECTIVE: To test whether CFs express TrkA that conveys paracrine signa...

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Autores principales: Aridgides, Daniel, Salvador, Ryan, PereiraPerrin, Mercio
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578799/
https://ncbi.nlm.nih.gov/pubmed/23437390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057450
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