Parasite-Derived Neurotrophic Factor/trans-Sialidase of Trypanosoma cruzi Links Neurotrophic Signaling to Cardiac Innate Immune Response

The Chagas' disease parasite Trypanosoma cruzi elicits a potent inflammatory response in acutely infected hearts that keeps parasitism in check and triggers cardiac abnormalities. A most-studied mechanism underlying innate immunity in T. cruzi infection is Toll-like receptor (TLR) activation by...

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Bibliographic Details
Main Authors: Salvador, Ryan, Aridgides, Daniel, PereiraPerrin, Mercio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187833/
https://ncbi.nlm.nih.gov/pubmed/24935974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02098-14
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