Essential function of HIPK2 in TGFβ-dependent survival of midbrain dopamine neurons

Transforming growth factor beta (TGFβ) is a potent trophic factor for midbrain dopamine (DA) neurons, but its in vivo function and signaling mechanisms are not entirely understood. We show that the transcriptional cofactor homeodomain interacting protein kinase 2 (HIPK2) is required for the TGFβ-med...

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Bibliographic Details
Main Authors:	Zhang, Jiasheng, Pho, Vanee, Bonasera, Stephen J, Holzmann, Jed, Tang, Amy T, Hellmuth, Joanna, Tang, Siuwah, Janak, Patricia H, Tecott, Laurence H, Huang, Eric J
Format:	Artigo
Language:	Inglês
Published:	2006
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3578579/ https://ncbi.nlm.nih.gov/pubmed/17159989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1816
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Essential function of HIPK2 in TGFβ-dependent survival of midbrain dopamine neurons

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