Loss of Mitochondrial Fission Depletes Axonal Mitochondria in Midbrain Dopamine Neurons

Disruptions in mitochondrial dynamics may contribute to the selective degeneration of dopamine (DA) neurons in Parkinson's disease (PD). However, little is known about the normal functions of mitochondrial dynamics in these neurons, especially in axons where degeneration begins, and this makes...

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Главные авторы: Berthet, Amandine, Margolis, Elyssa B., Zhang, Jue, Hsieh, Ivy, Zhang, Jiasheng, Hnasko, Thomas S., Ahmad, Jawad, Edwards, Robert H., Sesaki, Hiromi, Huang, Eric J., Nakamura, Ken
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205554/
https://ncbi.nlm.nih.gov/pubmed/25339743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0930-14.2014
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