Essential function of HIPK2 in TGFβ-dependent survival of midbrain dopamine neurons

Transforming growth factor beta (TGFβ) is a potent trophic factor for midbrain dopamine (DA) neurons, but its in vivo function and signaling mechanisms are not entirely understood. We show that the transcriptional cofactor homeodomain interacting protein kinase 2 (HIPK2) is required for the TGFβ-med...

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Detalhes bibliográficos
Main Authors: Zhang, Jiasheng, Pho, Vanee, Bonasera, Stephen J, Holzmann, Jed, Tang, Amy T, Hellmuth, Joanna, Tang, Siuwah, Janak, Patricia H, Tecott, Laurence H, Huang, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578579/
https://ncbi.nlm.nih.gov/pubmed/17159989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1816
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