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Peptide Immunization Elicits Polyomavirus-Specific MHC Class Ib-Restricted CD8 T Cells in MHC Class Ia Allogeneic Mice

Unlike the polymorphic MHC class Ia molecules, MHC class Ib molecules are oligomorphic or nonpolymorphic. We recently discovered a protective CD8 T cell response to mouse polyomavirus (MPyV) in H-2(b) haplotype mice that is restricted by H2-Q9, a member of the Qa-2 MHC class Ib family. Here, we demo...

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Detalhes bibliográficos
Main Authors: Hofstetter, Amelia R., Evavold, Brian D., Lukacher, Aron E.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578367/
https://ncbi.nlm.nih.gov/pubmed/23374150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2012.0052
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