Enhanced presentation of MHC class Ia, Ib and class II-restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy

BACKGROUND: Many peptide-based cancer vaccines have been tested in clinical trials with a limited success, mostly due to difficulties associated with peptide stability and delivery, resulting in inefficient antigen presentation. Therefore, the development of suitable and efficient vaccine carrier sy...

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Main Authors: Ma, Wenxue, Smith, Trevor, Bogin, Vladimir, Zhang, Yu, Ozkan, Cengiz, Ozkan, Mihri, Hayden, Melanie, Schroter, Stephanie, Carrier, Ewa, Messmer, Davorka, Kumar, Vipin, Minev, Boris
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078865/
https://ncbi.nlm.nih.gov/pubmed/21450109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-34
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