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Hairpin end conformation of adeno-associated virus (AAV) genome determines interactions with DNA repair pathways
The palindromic terminal repeats (TR) of adeno-associated virus (AAV) form DNA hairpins (HP) that are essential for replication and for priming the conversion of single-stranded virion DNA to double-strand. In recombinant AAV (rAAV) gene-delivery vectors, they are targets for DNA repair pathways lea...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578132/ https://ncbi.nlm.nih.gov/pubmed/23151519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2012.86 |
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