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Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin
The Ezrin-Radixin-Moesin (ERM) proteins regulate B lymphocyte activation via their effect on BCR diffusion and microclustering. This relies on their ability to dynamically tether the plasma membrane with actin filaments that is in turn facilitated by phosphorylation of the conserved threonine residu...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578034/ https://ncbi.nlm.nih.gov/pubmed/23338238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201292 |
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