Spatial coupling of JNK activation to the B cell antigen receptor by tyrosine-phosphorylated ezrin

The Ezrin-Radixin-Moesin (ERM) proteins regulate B lymphocyte activation via their effect on BCR diffusion and microclustering. This relies on their ability to dynamically tether the plasma membrane with actin filaments that is in turn facilitated by phosphorylation of the conserved threonine residu...

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Bibliographic Details
Main Authors: Parameswaran, Neetha, Enyindah-Asonye, Gospel, Bagheri, Nayer, Shah, Neilay B., Gupta, Neetu
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578034/
https://ncbi.nlm.nih.gov/pubmed/23338238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201292
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