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Profiling Two Indole-2-Carboxamides for Allosteric Modulation of the CB1 Receptor
Allosteric modulation of G-protein coupled receptors (GPCRs) represents a novel approach for fine-tuning GPCR functions. The cannabinoid CB1 receptor, a GPCR associated with the CNS, has been implicated in the treatment of drug addiction, pain, and appetite disorders. We report here the synthesis an...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578011/ https://ncbi.nlm.nih.gov/pubmed/23205875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12115 |
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