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Rheumatoid Factor B Cell Memory Leads to Rapid, Switched Antibody Forming Cell Responses
B cells are critical in the initiation and maintenance of lupus. Autoreactive B cells clonally expand, isotype switch and mutate—properties associated with memory B cells (MBC), which are typically generated via germinal centers (GCs). The development and functions of autoreactive MBC in lupus are p...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578004/ https://ncbi.nlm.nih.gov/pubmed/23365079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202816 |
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