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Significance and Suppression of Redundant IL17 Responses in Acute Allograft Rejection by Bioinformatics Based Drug Repositioning of Fenofibrate

Despite advanced immunosuppression, redundancy in the molecular diversity of acute rejection (AR) often results in incomplete resolution of the injury response. We present a bioinformatics based approach for identification of these redundant molecular pathways in AR and a drug repositioning approach...

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Détails bibliographiques
Auteurs principaux: Roedder, Silke, Kimura, Naoyuki, Okamura, Homare, Hsieh, Szu-Chuan, Gong, Yongquan, Sarwal, Minnie M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577752/
https://ncbi.nlm.nih.gov/pubmed/23437201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056657
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