Significance and Suppression of Redundant IL17 Responses in Acute Allograft Rejection by Bioinformatics Based Drug Repositioning of Fenofibrate

Despite advanced immunosuppression, redundancy in the molecular diversity of acute rejection (AR) often results in incomplete resolution of the injury response. We present a bioinformatics based approach for identification of these redundant molecular pathways in AR and a drug repositioning approach...

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Autores principales: Roedder, Silke, Kimura, Naoyuki, Okamura, Homare, Hsieh, Szu-Chuan, Gong, Yongquan, Sarwal, Minnie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577752/
https://ncbi.nlm.nih.gov/pubmed/23437201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056657
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