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Significance and Suppression of Redundant IL17 Responses in Acute Allograft Rejection by Bioinformatics Based Drug Repositioning of Fenofibrate

Despite advanced immunosuppression, redundancy in the molecular diversity of acute rejection (AR) often results in incomplete resolution of the injury response. We present a bioinformatics based approach for identification of these redundant molecular pathways in AR and a drug repositioning approach...

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Autors principals: Roedder, Silke, Kimura, Naoyuki, Okamura, Homare, Hsieh, Szu-Chuan, Gong, Yongquan, Sarwal, Minnie M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577752/
https://ncbi.nlm.nih.gov/pubmed/23437201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056657
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