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Cisplatin-Induced Apoptosis Inhibits Autophagy, Which Acts as a Pro-Survival Mechanism in Human Melanoma Cells

The interplay between a non-lethal autophagic response and apoptotic cell death is still a matter of debate in cancer cell biology. In the present study performed on human melanoma cells, we investigate the role of basal or stimulated autophagy in cisplatin-induced cytotoxicity, as well as the contr...

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Autors principals: Del Bello, Barbara, Toscano, Marzia, Moretti, Daniele, Maellaro, Emilia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577730/
https://ncbi.nlm.nih.gov/pubmed/23437349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057236
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