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Calpain-3 Impairs Cell Proliferation and Stimulates Oxidative Stress-Mediated Cell Death in Melanoma Cells

Calpain-3 is an intracellular cysteine protease, belonging to Calpain superfamily and predominantly expressed in skeletal muscle. In human melanoma cell lines and biopsies, we previously identified two novel splicing variants (hMp78 and hMp84) of Calpain-3 gene (CAPN3), which have a significant lowe...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Moretti, Daniele, Del Bello, Barbara, Allavena, Giulia, Corti, Alessandro, Signorini, Cinzia, Maellaro, Emilia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319969/
https://ncbi.nlm.nih.gov/pubmed/25658320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0117258
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