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Channel-mediated astrocytic glutamate release via Bestrophin-1 targets synaptic NMDARs
BACKGROUND: Astrocytes regulate neuronal excitability and synaptic activity by releasing gliotransmitters such as glutamate. Our recent study demonstrated that astrocytes release glutamate upon GPCR activation via Ca(2+) activated anion channel, Bestrophin-1 (Best1). The target of Best1-mediated ast...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3577500/ https://ncbi.nlm.nih.gov/pubmed/23324492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-4 |
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