Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors

BACKGROUND: Activation of G protein coupled receptor (GPCR) in astrocytes leads to Ca(2+)-dependent glutamate release via Bestrophin 1 (Best1) channel. Whether receptor-mediated glutamate release from astrocytes can regulate synaptic plasticity remains to be fully understood. RESULTS: We show here t...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Park, Hyungju, Han, Kyung-Seok, Seo, Jinsoo, Lee, Jaekwang, Dravid, Shashank M, Woo, Junsung, Chun, Heejung, Cho, Sukhee, Bae, Jin Young, An, Heeyoung, Koh, Woohyun, Yoon, Bo-Eun, Berlinguer-Palmini, Rolando, Mannaioni, Guido, Traynelis, Stephen F, Bae, Yong Chul, Choi, Se-Young, Lee, C Justin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4320468/
https://ncbi.nlm.nih.gov/pubmed/25645137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0097-y
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