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Protease activated receptor 1-induced glutamate release in cultured astrocytes is mediated by Bestrophin-1 channel but not by vesicular exocytosis

BACKGROUND: Glutamate is the major transmitter that mediates the principal form of excitatory synaptic transmission in the brain. It has been well established that glutamate is released via Ca(2+)-dependent exocytosis of glutamate-containing vesicles in neurons. However, whether astrocytes exocytose...

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Detalhes bibliográficos
Main Authors: Oh, Soo-Jin, Han, Kyung-Seok, Park, Hyungju, Woo, Dong ho, Kim, Hye Yun, Traynelis, Stephen F, Lee, C Justin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539998/
https://ncbi.nlm.nih.gov/pubmed/23062602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-5-38
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