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DNA methylation alterations exhibit intra-individual stability and inter-individual heterogeneity in prostate cancer metastases

Human cancers nearly ubiquitously harbor epigenetic alterations. While such alterations in epigenetic marks, including DNA methylation, are potentially heritable, they can also be dynamically altered. Given this potential for plasticity, the degree to which epigenetic changes can be subject to selec...

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Bibliografiske detaljer
Main Authors: Aryee, Martin J, Liu, Wennuan, Engelmann, Julia C, Nuhn, Philipp, Gurel, Meltem, Haffner, Michael C, Esopi, David, Irizarry, Rafael A, Getzenberg, Robert H, Nelson, William G, Luo, Jun, Xu, Jianfeng, Isaacs, William B, Bova, G Steven, Yegnasubramanian, Srinivasan
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577373/
https://ncbi.nlm.nih.gov/pubmed/23345608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3005211
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