Caricamento...

Structural basis of Wnt recognition by Frizzled

Wnts are lipid-modified morphogens that play critical roles in development principally through engagement of Frizzled receptors. The 3.25Å structure of Xenopus Wnt8 (XWnt8) in complex with mouse Frizzled-8 cysteine-rich domain (CRD) reveals an unusual two-domain Wnt structure, not obviously related...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Janda, Claudia Y., Waghray, Deepa, Levin, Aron M., Thomas, Christoph, Garcia, K. Christopher
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3577348/
https://ncbi.nlm.nih.gov/pubmed/22653731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1222879
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !