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Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Clostridium difficile infection is the most common cause of antibiotic-associated diarrhea in developed countries. The major virulence factor, C. difficile toxin B (TcdB), targets colonic epithelia by binding to frizzled (FZD) family of Wnt receptors, but how TcdB recognizes FZDs is unclear. Here we...
Gorde:
| Argitaratua izan da: | Science |
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| Egile Nagusiak: | , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6231499/ https://ncbi.nlm.nih.gov/pubmed/29748286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar1999 |
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