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Ing1 functions in DNA demethylation by directing Gadd45a to H3K4me3

Active DNA demethylation regulates epigenetic gene activation in numerous processes, but how the target site specificity of DNA demethylation is determined and what factors are involved are still poorly understood. Here we show that the tumor suppressor inhibitor of growth protein 1 (Ing1) is requir...

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Autors principals: Schäfer, Andrea, Karaulanov, Emil, Stapf, Ulrike, Döderlein, Gabi, Niehrs, Christof
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576512/
https://ncbi.nlm.nih.gov/pubmed/23388825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.186916.112
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