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Dysfunction of Inflammation-Resolving Pathways Is Associated with Exaggerated Postoperative Cognitive Decline in a Rat Model of the Metabolic Syndrome

The cholinergic antiinflammatory pathway (CAP), which terminates in the spleen, attenuates postoperative cognitive decline (PCD) in rodents. Surgical patients with metabolic syndrome exhibit exaggerated and persistent PCD that is reproduced in postoperative rats selectively bred for easy fatigabilit...

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Detalhes bibliográficos
Main Authors: Su, Xiao, Feng, Xiaomei, Terrando, Niccolo, Yan, Yan, Chawla, Ajay, Koch, Lauren G, Britton, Steven L, Matthay, Michael A, Maze, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576477/
https://ncbi.nlm.nih.gov/pubmed/23296426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00351
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