Surgery Results in Exaggerated and Persistent Cognitive Decline in a Rat Model of the Metabolic Syndrome

BACKGROUND: Postoperative cognitive decline can be reproduced in animal models. In a well-validated rat model of the Metabolic Syndrome, we sought to investigate whether surgery induced a more severe and persistent form of cognitive decline similar to that noted in preliminary clinical studies. METH...

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Detalhes bibliográficos
Publicado no:Anesthesiology
Main Authors: Feng, Xiaomei, Degos, Vincent, Koch, Lauren G., Britton, Steven L., Zhu, Yinggang, Vacas, Susana, Terrando, Niccolò, Nelson, Jeffrey, Su, Xiao, Maze, Mervyn
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5530762/
https://ncbi.nlm.nih.gov/pubmed/23353794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e318286d0c9
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