High Mobility Group Box 1 Contributes to the Pathogenesis of Experimental Pulmonary Hypertension via Activation of Toll-like Receptor 4

Survival rates for patients with pulmonary hypertension (PH) remain low, and our understanding of the mechanisms involved are incomplete. Here we show in a mouse model of chronic hypoxia (CH)-induced PH that the nuclear protein and damage-associate molecular pattern molecule (DAMP) high mobility gro...

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Bibliographische Detailangaben
Hauptverfasser: Bauer, Eileen M, Shapiro, Richard, Zheng, Han, Ahmad, Ferhaan, Ishizawar, David, Comhair, Suzy A, Erzurum, Serpil C, Billiar, Timothy R, Bauer, Philip M
Format: Artigo
Sprache:Inglês
Veröffentlicht: ScholarOne 2012
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3576475/
https://ncbi.nlm.nih.gov/pubmed/23269975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00283
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