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High Mobility Group Box 1 Inhibits Human Pulmonary Artery Endothelial Cell Migration via a Toll-like Receptor 4- and Interferon Response Factor 3-dependent Mechanism(s)

In pulmonary hypertension the loss of precapillary arterioles results from vascular injury causing endothelial dysfunction. Endothelial cell migration and proliferation are critical for vascular regeneration. This study focused on the effect of high mobility group box 1 protein (HMGB1) on these crit...

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Detalhes bibliográficos
Main Authors: Bauer, Eileen M., Shapiro, Richard, Billiar, Timothy R., Bauer, Philip M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543019/
https://ncbi.nlm.nih.gov/pubmed/23148224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434142
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