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High Mobility Group Box 1 Inhibits Human Pulmonary Artery Endothelial Cell Migration via a Toll-like Receptor 4- and Interferon Response Factor 3-dependent Mechanism(s)

In pulmonary hypertension the loss of precapillary arterioles results from vascular injury causing endothelial dysfunction. Endothelial cell migration and proliferation are critical for vascular regeneration. This study focused on the effect of high mobility group box 1 protein (HMGB1) on these crit...

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Autores principales: Bauer, Eileen M., Shapiro, Richard, Billiar, Timothy R., Bauer, Philip M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543019/
https://ncbi.nlm.nih.gov/pubmed/23148224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.434142
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