Extracellular High Mobility Group Box-1 (HMGB1) Inhibits Enterocyte Migration via Activation of Toll-like Receptor-4 and Increased Cell-Matrix Adhesiveness

Toll-like receptor-4 (TLR4) is the receptor for bacterial lipopolysaccharide, yet it may also respond to a variety of endogenous molecules. Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in newborn infants and is characterized by intestinal mucosal destru...

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Autors principals: Dai, Shipan, Sodhi, Chhinder, Cetin, Selma, Richardson, Ward, Branca, Maria, Neal, Matthew D., Prindle, Thomas, Ma, Congrong, Shapiro, Richard A., Li, Bin, Wang, James H.-C., Hackam, David J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836103/
https://ncbi.nlm.nih.gov/pubmed/20007974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067454
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