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Toll-like-receptor-4 Inhibits Enterocyte Proliferation via Impaired β-catenin Signaling in Necrotizing Enterocolitis

BACKGROUND AND AIMS: Necrotizing enterocolitis (NEC), the leading cause of gastrointestinal death from gastrointestinal disease in preterm infants, is characterized by exaggerated TLR4 signaling and decreased enterocyte proliferation through unknown mechanisms. Given the importance of β-catenin in r...

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Detalhes bibliográficos
Main Authors: Sodhi, Chhinder P., Shi, Xia-hua, Richardson, Ward M., Grant, Zachary S., Shapiro, Richard A., Prindle, Thomas, Branca, Maria, Russo, Anthony, Gribar, Steven C., Ma, Congrong, Hackam, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813409/
https://ncbi.nlm.nih.gov/pubmed/19786028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.09.045
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