Toll-like-receptor-4 Inhibits Enterocyte Proliferation via Impaired β-catenin Signaling in Necrotizing Enterocolitis

BACKGROUND AND AIMS: Necrotizing enterocolitis (NEC), the leading cause of gastrointestinal death from gastrointestinal disease in preterm infants, is characterized by exaggerated TLR4 signaling and decreased enterocyte proliferation through unknown mechanisms. Given the importance of β-catenin in r...

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Main Authors: Sodhi, Chhinder P., Shi, Xia-hua, Richardson, Ward M., Grant, Zachary S., Shapiro, Richard A., Prindle, Thomas, Branca, Maria, Russo, Anthony, Gribar, Steven C., Ma, Congrong, Hackam, David J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813409/
https://ncbi.nlm.nih.gov/pubmed/19786028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.09.045
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