Nucleotide-binding Oligomerization Domain-2 Inhibits Toll Like Receptor-4 Signaling in the Intestinal Epithelium

BACKGROUND & AIMS: Factors that regulate enterocyte apoptosis in necrotizing enterocolitis (NEC) remain incompletely understood, although Toll like receptor-4 (TLR4) signaling in enterocytes plays a major role. Nucleotide-binding-oligomerization domain-2 (NOD2) is an immune receptor that regulat...

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Hlavní autoři: Richardson, Ward M., Sodhi, Chhinder P., Russo, Anthony, Siggers, Richard H., Afrazi, Amin, Gribar, Steven C., Neal, Matthew D., Dai, Shipan, Prindle, Thomas, Branca, Maria, Ma, Congrong, Ozolek, John, Hackam, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930126/
https://ncbi.nlm.nih.gov/pubmed/20580721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2010.05.038
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